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NCI Drug Dictionary


A recombinant fusion protein derived from the coding sequences of two growth factors, interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF). Milodistim exhibits greater receptor binding affinity and colony stimulating activity than its parent cytokines. This agent stimulates proliferation of immature hematopoietic cells and allows the stimulation and expansion of multi-lineage hematopoiesis from immature bone marrow progenitor cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:GM-CSF/IL3 Fusion Protein
GM-CSF/IL-3 Fusion Protein
Granulocyte-Macrophage Colony Stimulating Factor/Interleukin-3 Fusion Protein
Code name:PIXY321