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NCI Drug Dictionary

NCI Drug Dictionary

  

recombinant human stem cell factor 
A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant human stem cell factor (rhSCF) binds to the receptor tyrosine kinase c-kit, which may stimulate the growth of peripheral blood progenitor cells (PBPCs). This agent works synergistically with other hematopoietic growth factors. rhSCF may promote bone marrow recovery after myeloablative therapies and procedures. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:c-kit ligand
mast-cell growth factor
recombinant methionyl human stem cell factor
r-metHuSCF
steel factor
US brand name:Ancestim
Acronym:rhSCF