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NCI Drug Dictionary

NCI Drug Dictionary

  

recombinant transforming growth factor-beta-2 
A recombinant polypeptide chemically identical to or similar to the endogenous cytokine transforming growth factor-beta-2 (TGF-beta-2). TGF-beta-2 modulates cell growth and immune function and may promote or inhibit tumor growth, depending on the tumor cell type. TGF-beta-2 may also suppress host immune system recognition of and/or response to tumor cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:glioblastoma-derived T-cell suppressor factor
transforming growth factor-beta 2
Abbreviation:rTGF-beta-2
Acronym:TGF-beta 2