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NCI Drug Dictionary


exemestane  Patient Information
A synthetic androgen analogue. Exemestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Aromasin
Abbreviation:PNU 155971
Code name:FCE-24304
Chemical structure:6-Methyleneandrosta-1,4-diene-3,17-dione