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NCI Drug Dictionary


rituximab  Patient Information
A recombinant chimeric murine/human antibody directed against the CD20 antigen, a hydrophobic transmembrane protein located on normal pre-B and mature B lymphocytes. Following binding, rituximab triggers a host cytotoxic immune response against CD20-positive cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:BI 695500
C2B8 Monoclonal Antibody
IDEC-C2B8 monoclonal antibody
rituximab biosimilar PF-05280586
rituximab biosimilar RTXM83
US brand name:Rituxan
Foreign brand name:Mabthera
Abbreviation:MOAB IDEC-C2B8
Code names:IDEC-102