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A recombinant chimeric murine/human antibody directed against the CD20 antigen, a hydrophobic transmembrane protein located on normal pre-B and mature B lymphocytes. Following binding, rituximab triggers a host cytotoxic immune response against CD20-positive cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|Synonyms:||BI 695500 |
C2B8 Monoclonal Antibody
IDEC-C2B8 monoclonal antibody
|US brand name:||Rituxan|
|Foreign brand name:||Mabthera|
|Code names:||IDEC-102 |