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NCI Drug Dictionary

NCI Drug Dictionary

  

recombinant adenovirus-p53 SCH-58500 
A genetically-engineered adenovirus that contains the gene that encodes the human tumor-suppressor protein p53 with potential antineoplastic activity. Recombinant adenovirus-p53 SCH-58500 delivers p53 into tumor cells, which may result in p53-mediated cell cycle arrest and apoptosis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Abbreviation:rAd/p53
Code name:SCH-58500