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NCI Drug Dictionary


dendritic cell-MART-1 peptide vaccine 
A cancer vaccine consisting of dendritic cells harvested from a patient with cancer and pulsed or transduced with a peptide fragment of MART-1 (melanoma antigen recognized by T-cells), an antigen expressed by melanoma cells. When the altered dendritic cells are returned to the patient, they stimulate the host immune system to mount a cytotoxic T-lymphocyte immune response against tumor cells expressing MART-1. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:MART-1 peptide-pulsed DC vaccine
MART-1 peptide-pulsed dendritic cell vaccine