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NCI Drug Dictionary

  

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An autologous cancer vaccine derived from tumor-specific gp96 heat shock proteins. Heat shock proteins chaperone peptides through the endoplasmic reticulum, are key regulators of dendritic cell maturation, migration and antigen processing, and are involved in T-cell activation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:autologous gp96 heat shock protein peptide complex vaccine
gp96 HSP-peptide complex
heat shock protein peptide complex-96
US brand name:Oncophage
Code name:HSPPC-96