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NCI Drug Dictionary


iodine I 131 tositumomab 
A monoclonal antibody directed against the CD20 protein expressed on the surface of B-lymphocytes and radiolabeled with the radioisotope iodine I 131 with potential antineoplastic activity. Iodine I 131 tositumomab binds to and selectively delivers cyctotoxic radiation to CD20-expressing B-lymphocytes, thereby minimizing systemic radiotoxicity. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:131-I-anti-B1 antibody
131-I-anti-B1 monoclonal antibody
iodine I 131 MOAB anti-B1
iodine I 131 monoclonal antibody anti-B1
iodine-131 anti-B1 antibody
iodine-131 anti-CD20 monoclonal antibody