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NCI Drug Dictionary


interferon alfacon-1 
An analogue of consensus interferon which contains an additional methionyl amino acid residue. Consensus interferon (also known as interferon alfacon-1, rCon-IFN, and CIFN) is a genetically engineered synthetic interferon created from the most common amino acid sequences from the naturally occurring alpha interferons. Alpha interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune-modulating effects. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:consensus interferon
IFN alfacon-1
interferon consensus, methionyl
methionyl interferon consensus
recombinant consensus interferon
recombinant methionyl human consensus interferon
US brand name:Infergen
Foreign brand name:Advaferon