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NCI Drug Dictionary


iodine I 131 monoclonal antibody 81C6 
A radioimmunoconjugate consisting of 81C6, a murine IgG2 anti-tenascin monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic activities. Using monoclonal antibody 81C6 as a carrier for I-131 results in the targeted imaging and/or destruction of cells expressing tenascin. Tenascin is an extracellular matrix protein which is overexpressed in gliomas and other cancers. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
I 131 Monoclonal Antibody 81C6
iodine I 131 MOAB 81C6
US brand name:Neuradiab