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A recombinant humanized monoclonal antibody directed against the vascular endothelial growth factor (VEGF), a pro-angiogenic cytokine. Bevacizumab binds to VEGF and inhibits VEGF receptor binding, thereby preventing the growth and maintenance of tumor blood vessels. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|Synonyms:||anti-VEGF humanized monoclonal antibody |
anti-VEGF monoclonal antibody
bevacizumab biosimilar BEVZ92
recombinant humanized anti-VEGF monoclonal antibody
|US brand name:||Avastin|
|Abbreviations:||rhuMAb VEGF |