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NCI Drug Dictionary


paclitaxel-loaded polymeric micelle 
A biodegradable poly(ethylene glycol)-poly(D,L-lactide) copolymer miceller nanoparticle-entrapped formulation of paclitaxel with antineoplastic activity. Paclitaxel promotes microtubule assembly and prevents depolymerization, thus interfering with normal mitosis. The copolymer residue increases the water-solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand names:Cynviloq™
Code name:IG-001