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NCI Drug Dictionary


dendritic cell-gp100-MART-1 antigen vaccine 
An autologous dendritic cell vaccine with antineoplastic property. Dendritic cells harvested from cancer patients are pulsed with human gp100 melanoma antigen and MART-1 antigen (a melanoma antigen recognized by T-cells); both antigens are up-regulated in melanomas. Vaccination with this vaccine may elicit the host immune response against MART-1 or gp100 expressing cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:gp100/Mart-1-transduced dendritic cell vaccine