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NCI Drug Dictionary


yttrium Y 90 epratuzumab 
A radioimmunoconjugate consisting of the anti-CD22 monoclonal antibody epratuzumab chelated to the radioisotope yttrium-90 (Y 90). Yttrium Y 90 epratuzumab binds to tumor cells expressing CD22, delivering a cytotoxic dose of beta radiation. Epratuzumab is a humanized version of the murine monoclonal antibody LL2; CD22 is a B cell-restricted antigen present on the surfaces of mature B cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:Y 90 Humanized Monoclonal Antibody LL2
Yttrium Y 90 Humanized Monoclonal Antibody LL2