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NCI Drug Dictionary

NCI Drug Dictionary

  

allogeneic dendritic cell-myeloma idiotype vaccine 
A cell-based vaccine composed of allogeneic dendritic cells pulsed ex-vivo with an autologous myeloma idiotype with potential antineoplastic activity. Upon administration, allogeneic dendritic cell-myeloma idiotype vaccine may stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against myeloma cells, resulting in cell lysis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)