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NCI Drug Dictionary

NCI Drug Dictionary

  

nadroparin calcium 
A low molecular weight heparin (LMWH) composed of a heterogeneous mixture of sulfated polysaccharide glycosaminoglycan chains obtained by depolymerisation of porcine mucosal sodium heparin, extraction/purification and conversion to the calcium salt. Nadroparin binds to antithrombin III (ATIII) and inhibits the activity of activated factor X (factor Xa), thereby inhibiting the final common pathway of the coagulation cascade and preventing the formation of a cross-linked fibrin clot. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:nadroparin
Foreign brand name:Fraxiparine