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NCI Drug Dictionary

NCI Drug Dictionary

  

dornase alfa inhalation solution 
A highly purified solution of recombinant human deoxyribonuclease I (rhDNAse) with selective DNA cleaving activity. Administrated through inhalation of the nebulized solution, dornase alpha catalyzes DNA degradation in viscous airway secretions, which may render airway secretions less viscous, thus promoting the clearing of airway mucous plugging and improvement in pulmonary function. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:recombinant human deoxyribonuclease I inhalation solution
US brand name:Pulmozyme
Foreign brand name:Pulmozyme
Abbreviation:rhDNase inhalation solution