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NCI Drug Dictionary


iodine-123 metaiodobenzylguanidine 
The neurotransmitter analogue 3-nitrobenzylguanidine conjugated to iodine I 123 and used as a gamma-emitting imaging agent. The adrenergic tissue uptake and storage of I-123 metaiodobenzylguanidine (I-123 MIBG) mimics that of norepinephrine (NE). The distribution of this agent enables the scintigraphic imaging of neural crest tumors, such as neuroblastoma and pheochromocytoma. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Abbreviation:I-123 MIBG