NCI Drug Dictionary
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indium In 111 girentuximab
A radioimmunoconjugate comprised of the chimeric monoclonal antibody girentuximab conjugated with the gamma-emitting radioisotope indium In 111. Indium In 111 girentuximab binds to G250, allowing the localization of G250-expressing tumor cells using gamma scintigraphy. Found in the majority of renal cell carcinomas (RCCs), G250 or carbonic anhydrase isozyme IX (CA IX) is a cell surface tumor-associated antigen (TAA). Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|Synonyms:||111-indium labeled chimeric monoclonal antibody G250 |
indium In 111 chimeric monoclonal antibody G250