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NCI Drug Dictionary


indium In 111 chimeric monoclonal antibody G250 
A radioimmunoconjugate comprised of the chimeric monoclonal antibody G250 conjugated with the gamma-emitting radioisotope indium In 111. Indium I 111 chimeric monoclonal antibody G250 binds to G250, allowing the localization of G250-expressing tumor cells using gamma scintigraphy. Found in the majority of renal cell carcinomas (RCCs), G250 or carbonic anhydrase isozyme IX (CA IX) is a cell surface tumor-associated antigen (TAA). Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:111-indium labeled chimeric monoclonal antibody G250