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NCI Drug Dictionary


autologous dinitrophenyl-modified ovarian cancer vaccine 
A cancer vaccine consisting of autologous ovarian cancer cell peptide antigens conjugated to the hapten 2,4-dinitrophenol (DNP) with potential immunostimulating and antineoplastic activities. Administration of autologous dinitrophenyl-modified ovarian cancer vaccine may induce a cytotoxic T-lymphocyte (CTL) response against ovarian cancer cells. DNP conjugation may enhance the immunogenicity of weakly immunogenic antigens. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:autologous DNP-modified ovarian cancer vaccine
US brand name:OVax