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NCI Drug Dictionary


ribonuclease QBI-139 
A nuclease of mammalian origin that cleaves the phosphodiester bond between nucleotides of ribonucleic acids with potential antineoplastic activity. Ribonuclease QBI-139 catalyzes the hydrolysis and degradation of RNA leading to the inhibition of protein synthesis and cell death. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Abbreviation:RNase QBI-139
Code name:QBI-139