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NCI Drug Dictionary


VEGFR2-targeted contrast agent BR55 
A lipopeptide-based, vascular endothelial growth factor receptor 2 (VEGRF2) -targeted contrast agent with the property of molecular imaging of angiogenesis. BR55 is prepared by incorporation of a biospecific heterodimer peptide into the perfluorobutane-containing lipid-shelled microbubble membrane; the peptide specifically binds to VEGFR2 expressed on tumoral vascular endothelium allowing ultrasound imaging of the sites of active angiogenesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Code name:BR55