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NCI Drug Dictionary


MELITAC 12.1 peptide vaccine 
A peptide cancer vaccine consisting of an emulsion of a mixture of 12 class I MHC-restricted melanoma peptides and a class II MHC-restricted tetanus toxoid helper peptide, with potential immunostimulating and antineoplastic activities. Upon administration, the MELITAC 12.1 peptide vaccine may stimulate the host immune system to mount a cytotoxic T-cell response against tumor cells expressing the melanoma peptide antigens, resulting in tumor cell lysis. The melanoma peptides contained in the vaccine are upregulated in melanoma cancer cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Code name:MELITAC 12.1