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NCI Drug Dictionary


A humanized monoclonal antibody directed against the C-epsilon 3 domain of immunoglobulin E. Olizumab binds to this IgE domain, thereby preventing IgE from binding to its high-affinity mast-cell receptor. Check for active clinical trials or closed clinical trials using this agent.
Synonyms:anti-IgE monoclonal antibody E25
US brand name:Xolair
Code name:IGE 025