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NCI Drug Dictionary

  

omalizumab 
A humanized monoclonal antibody directed against the C-epsilon 3 domain of immunoglobulin E. Olizumab binds to this IgE domain, thereby preventing IgE from binding to its high-affinity mast-cell receptor. Check for active clinical trials or closed clinical trials using this agent.
Synonyms:anti-IgE monoclonal antibody E25
olizumab
US brand name:Xolair
Abbreviation:rhuMAb-E25
Code name:IGE 025