NCI Drug Dictionary
A humanized monoclonal antibody directed against the C-epsilon 3 domain of immunoglobulin E. Olizumab binds to this IgE domain, thereby preventing IgE from binding to its high-affinity mast-cell receptor. Check for active clinical trials or closed clinical trials using this agent.
|Synonyms:||anti-IgE monoclonal antibody E25 |
|US brand name:||Xolair|
|Code name:||IGE 025|