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NCI Drug Dictionary


allogeneic irradiated melanoma cell vaccine CSF470 
An allogeneic cancer vaccine composed of a mixture of lethally irradiated whole melanoma cancer cells obtained from four different melanoma cell lines, with potential immunostimulating and antineoplastic activities. Upon intradermal injections, allogeneic irradiated melanoma cell vaccine may stimulate the body's immune system to exert a cytotoxic T-lymphocyte response and antibody-dependent cellular cytotoxicity (ADCC) against the melanoma cancer cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:CSF 470 vaccine
CSF470 vaccine