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NCI Drug Dictionary


nefopam hydrochloride 
The hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity. The mechanism of action through which nefopam exerts its analgesic effects is, as of yet, largely unknown but may involve inhibition of serotonin, dopamine and noradrenaline reuptake. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Chemical structures:1-ethyl-3-hydroxy-1-methylpyrrolidinium .alpha.-cyclopentylphenylacetate
3,4,5,6-tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride