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NCI Drug Dictionary

NCI Drug Dictionary

  

PEP-CMV vaccine 
A peptide vaccine derived from cytomegalovirus (CMV) antigens with potential immunostimulating activity. Intradermal administration of the PEP-CMV vaccine may stimulate the immune system to mount a specific helper and cytotoxic T-lymphocyte (CTL) response against CMV-infected tumor cells. Infection with the herpesvirus CMV may play a significant role in tumor cell initiation and progression as well as chemoresistance. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)