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NCI Drug Dictionary


glioma-associated peptide-loaded dendritic cell vaccine SL-701 
A cell-based cancer vaccine comprised of dendritic cells (DCs) pulsed with various synthetic glioma-associated antigen (GAA) peptides, with potential antineoplastic activity. Upon subcutaneous administration, the glioma-associated peptide-loaded DC vaccine SL-701 exposes the immune system to various GAA peptides. This may stimulate both anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against the GAA-expressing glioma cells, which may result in tumor cell lysis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Code name:SL-701