Established Investigator Award in Cancer Prevention and Control (K05)

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Please note: NCI no longer accepts applications for the K05. The Funding Opportunity Announcement expired on January 8, 2015, and will not be reissued.

The NCI Established Investigator Award in Cancer Prevention and Control (K05) provides established investigators protected time to:

  1. Conduct research in cancer prevention, control, behavioral sciences and population sciences, and
  2. Mentor junior investigators.

For more complete information, reference the Program Announcement and/or contact the program staff.

Applicant Eligibility


At the time of the award, the candidate must be:

  • a citizen of the United States,
  • or a noncitizen national,
  • or must have been lawfully admitted for permanent residence and possess an Alien Registration Receipt Card (1-151 or 1-551) or some other verification of legal admission as a permanent resident.

Citizenship or green card is not needed to apply. Citizenship or green card is needed at the time of award issuance.

Foreign Nationals with Student Visas Not eligible for this award
Degree/Academic Appointment Established Investigators (Full Professor or equivalent); at the time of application and award, the candidate must have independent R01 research funding or its equivalent
Effort Level/ Commitment The candidate may commit up to 3 calendar months (25%) full-time professional effort to the research and mentoring proposed in this award.
Duration of Award 3 - 5 years

Special NCI Eligibility Requirements

The candidate must be the Principal Investigator (PI) of an R01, or R01-like, peer-reviewed cancer-focused research grant at the time of application and during the award to be eligible for the K05 Award.

For the NCI K05, R01-like research funding includes peer-reviewed research grants from other federal sources and private foundations. The award duration must be for at least 3 years with a minimum of $150,000 direct costs per year. Grants under a no-cost extension do not qualify.

The PI is expected to maintain such research grant support during the K05 project period. If the awardee loses peer-reviewed independent research support during the K05 Award period, the awardee must document efforts to replace this support and demonstrate that he or she continues to meet all other requirements of the K05 Award.


Financial Support
Salary Up to $50K/year + fringe benefits
Research Development Support for Mentees: Tuition/Fees, Supplies/Equipment, Travel, Technical Personnel and Statistical Services Up to $25K/year
F&A Costs/ Indirect Costs 8%
Ancillary Personnel Support: Salary for Secretarial and Administrative Assistance, etc. Not allowed

How to Apply

K05 applications are no longer accepted.

Application Receipt Dates and Review Schedule
Receipt Cycle Receipt Date: New Application Receipt Date: Renewal, Resubmission Application Initial Review Council Review Earliest Possible Start Date*
1 February 12 March 12 June/July September/
2 June 12 July 12 October/November January/
3 October 12 November 12 February/March May/June July

* Start dates are determined by the availability of NCI funds and may not occur until well after the earliest possible start date.

Review and Selection Process

The Center for Scientific Review (CSR) and the National Cancer Institute (NCI) review applications for completeness and for conformance to all eligibility requirements and special provisions and requirements. Incomplete applications will be returned to the applicant without further consideration.

Subcommittee J, convened by the Division of Extramural Activities of the NCI, evaluates applications according to the review criteria listed in the Program Announcement. Before an award is made, the National Cancer Advisory Board (NCAB) conducts a second level of review and ensures that an application meets the broad program needs and priorities of the NCI and the National Cancer Program.

For review criteria for the K05 grant mechanism, see the Review Criteria section of the Program Announcement.

Find an overview of the grant process


NCI Staff Contacts

For additional information regarding policies and/or guidance in preparing an application for the K05 Award, contact:

For information regarding fiscal and/or budget issues, contact:

For information regarding review issues, contact:

  • Referral Officer
    Division of Extramural Activities
    Phone: 240-276-6390
  • Updated: February 11, 2015