NCI Drug Dictionary

  • Resize font
  • Print
  • Email
  • Facebook
  • Twitter
  • Google+
  • Pinterest

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

ipilimumab
Patient Information A monoclonal antibody directed against cytotoxic T-lymphocyte-associated antigen-4 (CTLA4), an antigen that is expressed on activated T-cells and exhibits affinity for B7 co-stimulatory molecules. By binding CTLA4, ipilimumab enhances T-cell activation and blocks B7-1 and B7-2 T-cell co-stimulatory pathways. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms:anti-cytotoxic T-lymphocyte-associated antigen-4 monoclonal antibody
MOAB CTLA-4
monoclonal antibody CTLA-4
US brand name:Yervoy
Abbreviation:MDX-CTLA-4
Code names:BMS-734016
MDX-010