NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

bromodeoxyuridine
A halogenated thymidine analogue with potential antineoplastic and radiosensitizing activities. Bromodeoxyuridine competes with thymidine for incorporation into DNA, resulting in DNA mutation and the inhibition of cell proliferation. As a radiosensitizer, this agent is associated with the inhibition of repair of radiation-induced DNA double-strand breaks (DSBs). Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms:5-bromodeoxyuridine
broxuridine
Abbreviations:5-BrdU
BrdU
Chemical structure:5-bromouracil-2-deoxyriboside