vindesine sulfate
The sulfate salt form of Vindesine. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI)
Synonym: | desacetyl vinblastine amide sulfate vindesine sulphate vindesini sulfas |
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US brand name: | Eldisine |
Foreign brand name: | Eldesine Eldisin Enison Fildesin Gesidine |
Code name: | LY-099094 |