NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

Patient Information A recombinant humanized monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2). After binding to HER2 on the tumor cell surface, trastuzumab induces an antibody-dependent cell-mediated cytotoxicity against tumor cells that overexpress HER2. HER2 is overexpressed by many adenocarcinomas, particularly breast adenocarcinomas. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
anti-c-erbB2 monoclonal antibody
anti-erbB2 monoclonal antibody
anti-HER2/c-erbB2 monoclonal antibody
Herceptin biosimilar PF-05280014
Herceptin trastuzumab biosimilar PF-05280014
monoclonal antibody c-erb-2
monoclonal antibody HER2
trastuzumab biosimilar ABP 980
trastuzumab biosimilar PF-05280014
trastuzumab biosimilar SB3
US brand name:Herceptin
Abbreviations:MOAB HER2
rhuMAb HER2
Code names:ABP 980