NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

mesalamine
An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. Check for active clinical trials using this agent.
Synonym:mesalazine
US brand names:Apriso
Asacol
Lialda
Pentasa
Rowasa
Abbreviation:5-ASA
Chemical structures:5-amino-2-hydroxybenzoic acid
5-aminosalicylic acid