NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms: diazoacetate (ester) L-Serine
diazoacetic acid ester with serine
Code names: CL-337
Chemical structures: L-diazoacetate (ester) serine
L-serine diazoacetate (ester)