NCI Dictionary of Cancer Terms
The NCI Dictionary of Cancer Terms features 7,790 terms related to cancer and medicine.
Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.
- listen (MEH-kih-nist)
A drug used alone or with dabrafenib to treat melanoma that cannot be removed by surgery or has spread to other parts of the body. It is used in patients with a mutated (changed) form of a cell protein called BRAF. It is also being studied in the treatment of other types of cancer. Mekinist blocks certain proteins, which may help keep cancer cells from growing and may kill them. It is a type of kinase inhibitor and a type of targeted therapy. Also called trametinib.