Introduction
The purpose of the Paul Calabresi Career Development Award for Clinical Oncology (PCACO) K12 (NIH Institutional Research Career Development K12 grant mechanism) is to increase the number of clinicians (M.D.s, D.O.s, Pharm.D.s, nurses with Ph.D.s or equivalent) and Ph.D. scientists who are trained to design and test clinical therapeutic research protocols (pilot/Phase I, Phase II, and Phase III clinical trials), conduct patient-oriented cancer therapeutic research in team research environments, and to support the career development of investigators who have made a commitment to focus their research endeavors on patient-oriented research. A PCACO can support the research career development of senior fellow and/or junior faculty level clinicians (single track) or senior fellow and/or junior faculty level clinicians and postdoctoral Ph.D. scientists (dual track). Clinical and Ph.D. scientists will collaborate and interact to expedite the translation of basic science research discoveries into patient-oriented therapeutic cancer research. The PCACO is not intended to train scientists for laboratory based research. The PCACO provides up to 5 years of support and is renewable.
For more complete information, reference the program announcement and/or contact the program staff.
PI Eligibility
| Citizenship | At the time of the award, the PI must be a U.S.citizen or must have been lawfully admitted to the United States for permanent residence (i.e., in possession of a currently valid Alien Registration Receipt Card (1-151 or 1-551), or other legal verification of such status). |
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| Career Stage | Established Investigators (Associate and Full Professors). Expected to have ongoing R01 and/or R01-like cancer focused grant support. (For the K12 program, R01 and/or R01-like awards are grants or contracts of at least 3 years and $150,000/year in direct costs, including those supporting clinical trials). |
Mentor Eligibility
| Career Stage | Researchers from diverse backgrounds are encouraged to participate as mentors. Expected to have independent R01 and/or R01-like cancer related research support. (For the K12 program, R01 and/or R01-like awards are grants or contracts of at least 3 years and $150,000/year in direct costs, including those supporting clinical trials). |
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Scholar Eligibility
| Citizenship | At the time of the award, the PI must be a U.S.citizen or must have been lawfully admitted to the United States for permanent residence (i.e., in possession of a currently valid Alien Registration Receipt Card (1-151 or 1-551), or other legal verification of such status). |
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| Career Stage | Candidates or trainees must be physicians holding the M.D. or D.O. degrees, Pham.D. recipients, nurses with a Ph.D. or equivalent degree, and must have completed the necessary clinical training (i.e., completed residency and are board eligible) to engage in clinical oncology research. All basic science candidates must have doctoral-level degrees (e.g., Ph.D.) or the equivalent, a minimum of 2 years of postdoctoral research training, and a basic research experience that is clearly preparatory (e.g., experience with animal models or preclinical research) for devoting a career to human therapeutic cancer research. |
| MD: PhD Ratio | 2:1 |
| Commitment | Candidate must commit a minimum 9.0 calendar months (75% of full-time professional effort) to research and career development. Candidates who have U.S. Veterans’ Administration (VA) appointments may not consider part of the VA effort toward satisfying the “full time” requirement at the applicant institution. |
| Duration of Award | 2 to 4 yrs of support. |
K12 Program Allowable Costs
| Direct Cost limits: | All applications must not exceed $750,000 for direct costs per year. The first year’s direct costs budget is capped at $50,000. This first year is for advertising and recruitment of Scholars, Advisory Board(s) recruitment and meeting, curriculum planning and development and development of individual Scholar’s curricula. |
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| Personnel Support | Up to $10,000 total per annum may be allocated for all PDs/PIs of the K12 programs to partially offset their salaries and associated fringe benefit costs, depending on commitment of effort. The costs of a consultant, Program Administrator and/or program assistant with responsibilities directly associated with the institutional career development program can be requested with justification. |
| F & A costs/Indirect costs | 8% |
Financial Support for each K12 Fellow
| Salary | Up to $100K/ yr + fringe benefits |
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| Research Development Support | Up to $30K/ yr |
Program Announcement & Related Links
| Program Announcement | http://grants.nih.gov/grants/guide/pa-files/PAR-13-201.html |
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| NCI Special Notes | http://www.cancer.gov/researchandfunding/cancertraining/outsidenci/K12/specialnotes/NCI-K12-Special-Institutional-Statement.pdf |
| Current List of K12 Awards | Funded Active K12 |
| Link of Peer Review Groups F | http://era.nih.gov/roster/proster.cfm?CID=100453 |
| Application Form and Details | http://grants.nih.gov/grants/funding/424/index.htm |
| Notices | http://grants.nih.gov/grants/guide/notice-files/NOT-CA-09-022.html |
