St. Jude Children's Research Hospital Memphis, Tennessee
St. Jude Children’s Research Hospital was founded in 1962. The Cancer Center received its NCI designation in 1977 and was awarded status as a comprehensive cancer center by NCI in 2008. The hospital’s mission is to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment.
St. Jude has a staff of more than 3,600, including over 150 researchers who are part of the Cancer Center. They are engaged in a broad spectrum of research, including discovery-oriented basic science research, the investigation of disease pathogenesis and drug resistance, biobehavioral and quality-of-life research, and therapeutic trials.
The Cancer Center supports six major interdisciplinary research programs. The Molecular Oncology and Signal Transduction program focuses on basic, discovery-oriented research. The programs for Developmental Therapeutics for Solid Malignancies, Hematological Malignancies, Neurobiology and Brain Tumor, and the Cancer Prevention and Control all emphasize the translation of laboratory or population science into clinical applications. The Prevention and Control effort also represents St. Jude’s commitment to long-term follow-up of cancer patients, as well as a commitment to population sciences. There is an After Completion of Therapy Clinic for children who have been treated at St. Jude.
Recent expansions of the immunology faculty and the Chemical Biology and Therapeutics faculty have also broadened the scope of cancer research. A new collaboration is the Pediatric Cancer Genome Project, a joint research initiative in pediatric cancer between St. Jude and the Genome Center of Washington University in St. Louis, Missouri. A team drawn from the two institutions has joined forces to decode the complete genomes of more than 600 childhood cancer patients who have contributed tumor samples for this effort.
The children who are accepted for cancer treatment at St. Jude are treated on disease-specific frontline protocols developed by Cancer Center investigators. The hospital also accepts children who have already been treated elsewhere and are eligible for transplantation, relapse, or Phase I or II clinical trials. Several major multi-institutional studies are centered at St. Jude, including the NCI-funded Childhood Cancer Survivors Study and the Pediatric Brain Tumor Consortium.
Education programs at St. Jude include lectures, symposiums and the preparation of curriculum for the local pediatric practitioner community. Residents and students are part of the fabric of life at St. Jude.
Outreach programs range from the local community to international partnerships, such as the St. Jude International Outreach Program with partnerships in 20 formal sites around the world. The program brings the latest advances in pediatric cancer to developing countries through web-based initiatives, education of local health care providers, and the establishment of pediatric cancer clinics in areas with limited local resources. The http://www.Cure4Kids.org website is dedicated to supporting the care of children with cancer and other catastrophic diseases worldwide. Closer to home, St. Jude’s outreach efforts include programs in schools and hospitals.
* This profile was provided by the St. Jude Children's Research Hospital.