UAB Comprehensive Cancer Center University of Alabama at Birmingham Birmingham, Alabama
Established in 1971, the University of Alabama at Birmingham Comprehensive Cancer Center (UAB), received its NCI designation in the same year. The Center has grown to include a membership of more than 330 physicians and researchers.
The vision of the UAB Comprehensive Cancer Center is to eliminate cancer as a major public health problem. The mission of the Center is to provide the highest quality of life for people diagnosed with cancer, while advancing the understanding of cancer and translating this knowledge into improved prevention, detection, treatment, and survivorship.
Areas of research emphasis include gene therapy, immunotherapy, and drug discovery and development. Advances by UAB CCC scientists and physicians have come in the areas of chemotherapy, surgery, radiotherapy, immunotherapy, and nutrition. In addition, scientists at the Center are developing innovative monoclonal antibody approaches to cancer therapy.
The Center has a major strength in translational research, with active programs of research and patient care in breast, ovarian, brain, and pancreatic cancers. Patient care is delivered in multidisciplinary clinics that also foster accrual to clinical trials with novel treatments, using genetically-engineered monoclonal antibodies alone or in combination with immunotoxins, chemotherapy, or radioactive isotopes to specifically target a broad array of cancers.
The team at the UAB CCC is developing a series of cancer vaccine trials using genetically-engineered vaccine reagents. The Center has developed a number of therapeutic vaccine strategies. As an overall vaccine strategy, UAB is exploring a broad array of approaches to induce an immune response to molecules prevalent in tumor cells.
Outreach and collaboration are hallmarks of the Deep South Network for Cancer Control, a UAB program that focuses on training, data gathering, and educational outreach in 22 counties in Alabama and the Mississippi Delta. The Center has held hundreds of community events on the importance of cancer prevention, awareness, and cancer screening. UAB uses trained volunteers as Community Health Advisors to educate community members.
The goal of the Deep South Network is to build a community infrastructure that will aid in eliminating cancer health disparities in underserved African American communities. Collaboration with local communities has resulted in Network collaborations with more than 300 community partners including small businesses, industries, schools, faith-based groups, and other organizations to implement cancer prevention and wellness programs. Media partners, not-for-profit organizations, and state agencies assist the Deep South Network in disseminating information to local communities.
* This profile was provided by the University of Alabama Comprehensive Cancer Center.