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This page contains brief information about the drug combination called FOLFIRINOX. The drugs in the combination are listed, and links to individual drug summaries are included.

Drugs in the FOLFIRINOX combination:
FOL = Leucovorin Calcium (Folinic Acid)
F = Fluorouracil
IRIN = Irinotecan Hydrochloride
OX = Oxaliplatin

Chemotherapy is often given as a combination of drugs. Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.

Each of the drugs in this combination is approved by the Food and Drug Administration (FDA) to treat cancer or conditions related to cancer.

Use in Cancer

FOLFIRINOX is used to treat:

This combination may also be used with other drugs or treatments or to treat other types of cancer.


Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

Research Results

Clinical Trial Results: Chemotherapy Regimen Extends Survival in Advanced Pancreatic Cancer Patients - Important clinical trial results for this drug, background information, and how the trial was done.

  • Posted: November 28, 2011
  • Updated: May 29, 2012