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Coordinating Center for Clinical Trials

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About CCCT

Overview

The Coordinating Center for Clinical Trials (CCCT) was established in 2006 and resides within the NCI's Office of the Director. Its overarching goal is to strengthen NCI's clinical trials and translational research enterprises– cooperative endeavors that draw upon the strongest components of its clinical research system, the Institute's scientific infrastructure, and constant engagement of critical stakeholders. 

CCCT guides the implementation of recommendations made by the National Cancer Advisory Board's (NCAB)'s Clinical Trials Working Group (CTWG) and Translational Research Working Group (TRWG).  This is achieved through continuing dialogue with NCI leadership and scientific staff, clinicians, researchers, advocates, policymakers, industry, and foundations, in order to enhance the effectiveness of our nation's cancer clinical research enterprise.

The CCCT oversees implementation of the 22 initiatives recommended by the CTWG in 2005 as well as 15 initiatives recommended by the TRWG in 2007.

CCCT Mission Statement

CCCT org graphic

CCCT facilitates an ongoing dialogue between the Institute's various divisions, offices, and centers, represented by CTROC, and the extramural clinical and translational research communities, represented by CTAC. View PDF of graphic (280 kb)

The CCCT is central to NCI's efforts to accelerate the delivery of new tools into the clinic through its translational science and clinical trial enterprises. In conjunction with all NCI divisions, offices, and centers, CCCT facilitates collaborations that expedite translational and clinical cancer research by: 

  • Supporting the implementation of the CTWG and TRWG recommendations;
  • Facilitating prioritization of the NCI's most important clinical trials by Scientific Steering Committees working with NCI clinical programs, such as those in the Division of Cancer Treatment and Diagnosis and the Division of Cancer Prevention;
  • Partnering with the NCI's Center for Biomedical Informatics and Information Technology (CBIIT) to establish the Clinical Trials Reporting Program (CTRP), a comprehensive database with up-to-date information on all NCI-funded clinical trials;
  • Managing the CTROC and the CTAC, which advise NCI leadership on translational science and clinical trials.
  • CCCT facilitates an ongoing dialogue between the Institute's various divisions, offices, and centers, represented by CTROC, and the extramural clinical and translational research communities, represented by CTAC.