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Coordinating Center for Clinical Trials

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Advisory Committees

The CCCT consults with the advisory bodies described below in order to enhance NCI's clinical trials and translational research enterprises.  

Clinical Trials and Translational Research Advisory Committee (CTAC)

The CTAC is an external oversight committee that advises NCI leadership on ways to strengthen NCI's clinical and translational research enterprises, including both intramural and extramural research. The CTAC is composed of leading authorities across the entire continuum of cancer research, prevention, and treatment. The committee advises NCI leadership on ways to build strong scientific infrastructures that engage a broad coalition of stakeholders involved in the clinical trials and translational research processes. CTAC is chaired by the NCI director, the CCCT director serves as the executive secretary, and the CCCT staff facilitates operations.

Roles and responsibilities of the CTAC include:

  • Oversees implementation of the CTWG and TRWG recommendations and initiatives, including evaluation systems.
  • Provides strategic advice regarding NCI's entire clinical trials and translational research portfolios.
  • Advises NCI on policies, procedures, processes, and tools that should be developed and implemented for prioritization, management, coordination, and administration of NCI-funded clinical trials and translational research.
  • Advises the NCI director on the status of NCI clinical trials and translational research projects across all divisions, offices, and centers and makes recommendations for needed improvements.
  • Provides a forum for the clinical trials and translational research communities to give advice directly to the NCI director.

For information on CTAC's membership, charter, function statement, meeting schedule, agendas, and meeting summaries, please visit the CTAC web site.

Clinical and Translational Research Operations Committee (CTROC)

The CTROC is an internal NCI advisory committee composed of representatives from NCI divisions, offices, and centers involved in NCI-supported clinical trials and translational research. The committee reviews and prioritizes NCI-supported clinical trials, correlative science programs, and translational research. The CCCT staff coordinates CTROC operations.