Leucovorin Calcium

  (LOO-koh-VOR-in KAL-see-um)

This page contains brief information about leucovorin calcium and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s):		Wellcovorin
FDA Approved:		Yes

Use in Cancer

Leucovorin calcium is approved to be used alone or with other drugs to treat:

• Colorectal cancer. It is used with fluorouracil as palliative treatment in patients with advanced disease.

• Anemia. It is used to treat megaloblastic anemia that occurs when the body does not get enough of a vitamin called folic acid. It is used by patients who cannot take the vitamin by mouth.

Leucovorin calcium is also used to prevent and treat the toxic effects of high dose methotrexate when used to treat osteosarcoma and other types of cancer. It is also used to treat overdoses of methotrexate or other folic acid antagonists.

The drug is also being studied in the treatment of other conditions and types of cancer.

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Leucovorin Calcium - A lay language summary of important information about this drug that may include the following:

• warnings about this drug,
• what this drug is used for and how it is used,
• what you should tell your doctor before using this drug,
• what you should know about this drug before using it,
• other drugs that may interact with this drug, and
• possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Clinical Trial Results: Irinotecan Not Effective in Adjuvant Therapy for Colon Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: New Chemotherapy Regimen Extends Survival for Patients with Resectable Gastric Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Find Clinical Trials for Leucovorin Calcium - Check for trials from NCI's list of cancer clinical trials now accepting patients.

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