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Melanoma: Treatment

Information Summaries from PDQ

Drug Information

  • Drugs Approved for Melanoma

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for melanoma. The list includes generic names and brand names.

Clinical Trials

  • Clinical Trials to Treat Melanoma

    Check for melanoma treatment trials from NCI's list of cancer cllinical trials now accepting patients. The list of clinical trials can be refined by location, stage of disease, drug, and other features.

  • Clinical Trials to Treat Intraocular (Eye) Melanoma

    Check for intraocular (eye) melanoma treatment trials from NCI's list of cancer trials now accepting patients. The list of clinical trials can be refined by location, stage of disease, drug, and other features.

Research Findings

  • New Therapies Are Changing the Outlook for Advanced Melanoma

    In the last several years, after decades of little progress, a host of new treatment options have been produced for patients with the skin cancer melanoma. Since 2011, the FDA has approved six new treatments for advanced melanoma that has spread to other parts of the body. And the progress is showing no signs of slowing.

  • MEK: A Single Drug Target Shows Promise in Multiple Cancers

    Drugs that block the MEK protein have shown promise in several cancers. Trametinib has had encouraging results in patients with advanced melanoma, and selumetinib has been tested in patients with advanced thyroid and ovarian cancers.

Related Treatment Information

  • Sentinel Lymph Node Biopsy

    A fact sheet that describes the sentinel lymph node biopsy (SLNB) procedure, its use in determining the extent, or stage, of cancer in the body, and the results of research on the use of SLNB in breast cancer and melanoma.

  • Angiogenesis Inhibitors

    A fact sheet that describes the process of eliminating the blood supply to tumors. Lists the cancers in which this approach is being tested.

  • Biological Therapies for Cancer

    A fact sheet that provides an overview of how the immune system functions and describes the actions of biological therapies, such as monoclonal antibodies, cytokines, therapeutic vaccines, the bacterium bacillus Calmet-Guérin, cancer-killing viruses, gene therapy, and adoptive T-cell transfer.

  • Targeted Cancer Therapies

    A fact sheet that describes targeted cancer therapies, which are drugs that interfere with specific molecules involved in cancer cell growth and survival.

  • Metastatic Cancer

    A fact sheet about metastasis, the spread of cancer to other parts of the body. Discusses the diagnosis and treatment of cancer that has spread.