Information Summary from PDQ
- Clinical Trials to Treat Prostate Cancer
Check for prostate cancer treatment trials from NCI's list of cancer clinical trials now accepting patients. The list of clinical trials can be refined by location, stage of disease, drug, and other features.
General Information About Prostate Cancer Treatment
- Panel Encourages Broader Use of Surveillance in Some Men with Prostate Cancer
An independent panel of experts has endorsed delaying treatment, at least for a time, for many men who are diagnosed with forms of prostate cancer that likely pose no risk to long-term health.
- Drugs Approved for Prostate Cancer
This page lists cancer drugs approved by the Food and Drug Administration (FDA) for prostate cancer. The list includes generic names and brand names.
- Hormone Therapy for Prostate Cancer
A fact sheet that describes hormone therapy and its role in treating prostate cancer. Includes information about the different types of hormone therapy, how they are used, and possible side effects.
- Treatment Choices for Men With Early-Stage Prostate Cancer
This booklet describes the treatment choices available to men diagnosed with early-stage prostate cancer.
- NIH-funded study shows increased survival in men with metastatic prostate cancer who receive chemotherapy when starting hormone therapy
Men with hormone-sensitive metastatic prostate cancer who received the chemotherapy drug docetaxel given at the start of standard hormone therapy lived longer than patients who received hormone therapy alone, according to early results from a NIH-supported randomized controlled clinical trial.
- Radium-223 Improves Survival in Patients with Advanced Prostate Cancer
Results from a phase III trial show that radium-223 dichloride (Xofigo®) improves overall survival in men with advanced prostate cancer that has spread to their bones compared with placebo.
- Observation as Good as Surgery for Some Men with Prostate Cancer
Many men diagnosed with early-stage prostate cancer could forego radical prostatectomy and live as long as men who have immediate surgery, according to long-awaited results from a clinical trial published July 19, 2012, in the New England Journal of Medicine (NEJM).
- Abiraterone Improves Survival in Metastatic Prostate Cancer
A multinational phase III trial found that the drug abiraterone acetate prolonged the median survival of patients with metastatic castration-resistant prostate cancer by 4 months compared with patients who received a placebo.
- NIH-funded study shows reduction in death for men with intermediate-grade prostate cancer:
Short-term hormone therapy given in combination with radiation therapy to men with early-stage prostate cancer increased their chances of living longer compared to treatment with radiation therapy alone, according to a clinical trial supported by NCI. Benefits of the combined treatment were limited mainly to patients with intermediate-risk disease and were not seen for men with low-risk prostate cancer, researchers say.
- Denosumab Reduces Risk of Bone Side Effects in Advanced Prostate Cancer
The biological agent denosumab (Xgeva) is more effective than zoledronic acid at decreasing the risk of bone fractures and other skeletal-related events (SRE) in men with castration-resistant metastatic prostate cancer, according to results from a randomized clinical trial reported online February 25, 2011, in The Lancet.
Related Treatment Information
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- Metastatic Cancer
A fact sheet about metastasis, the spread of cancer to other parts of the body. Discusses the diagnosis and treatment of cancer that has spread.