Prevention Clinical Trials for Prostate Cancer

Clinical trials are research studies that involve people. The clinical trials on this list are for prostate cancer prevention. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-4 of 4
  • Home-Based Exercise Program in Studying Impact on Prognostic Biomarkers in Participants with Prostate Cancer

    This pilot trial studies the impact of a home-based exercise program on prognostic biomarkers in participants with prostate cancer. Several reports suggest that physical activity after a cancer diagnosis is associated with better cancer-specific and overall survival in individuals diagnosed with prostate cancer. A home-based exercise program may help doctors to learn the impact of exercise on blood markers associated with tumor development and the effect of exercise on the biology of prostate cancer, its impact on fatigue, and quality of life in participants with prostate cancer.
    Location: Cancer Therapy and Research Center at The UT Health Science Center at San Antonio, San Antonio, Texas

  • Taste Acceptability of Tomato-Soy-Arugula Seed Beverages in Preventing Recurrence in Patients with Prostate Cancer

    This clinical trial studies whether the taste of tomato-soy-arugula seed beverages is acceptable to patients with prostate cancer. Eating a diet rich in tomatoes and other vegetables has been associated with decreased risk of a variety of diseases, including prostate cancer. Mixed vegetable beverages may help to reduce the risk of prostate cancer coming back after initial therapy.
    Location: Ohio State University Comprehensive Cancer Center, Columbus, Ohio

  • Rilimogene Galvacirepvec and Recombinant Fowlpox-PSA(L155) / TRICOM Vaccine in Preventing Relapse in Patients with Prostate Cancer after Radical Prostatectomy

    This phase II trial studies how well rilimogene galvacirepvec and recombinant fowlpox-prostate specific antigen (PSA)(L155) / triad of costimulatory molecules (B7-1, ICAM-1 and LFA-3) (TRICOM) vaccine work in preventing prostate cancer from coming back in patients who have undergone radical prostatectomy. Vaccines made from a gene-modified virus such as, rilimogene galvacirepvec and recombinant fowlpox-PSA(L155) / TRICOM vaccine, may help the body build an effective immune response to kill tumor cells. Giving vaccine after surgery may kill any remaining tumor cells.
    Location: 2 locations

  • Low-Fat Diet and Fish Oil in Men on Active Surveillance for Prostate Cancer

    This randomized phase II trial will evaluate if a low-fat diet with fish oil has the potential to delay disease progression in patients with prostate cancer undergoing active surveillance.
    Location: 2 locations