Prevention Clinical Trials for Prostate Cancer

Clinical trials are research studies that involve people. The clinical trials on this list are for prostate cancer prevention. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-6 of 6
  • Diet and Exercise Interventions in Improving Outcomes in Men with Prostate Cancer

    This phase II trial studies how well diet and exercise interventions work in improving biological, clinical, and quality of life outcomes in men with prostate cancer undergoing radical prostatectomy. Following diet and exercise interventions may prevent the prostate cancer from coming back or progressing.
    Location: 3 locations

  • Rilimogene Galvacirepvec and Recombinant Fowlpox-PSA(L155) / TRICOM Vaccine in Preventing Relapse in Patients with Prostate Cancer after Radical Prostatectomy

    This phase II trial studies how well rilimogene galvacirepvec and recombinant fowlpox-prostate specific antigen (PSA)(L155) / triad of costimulatory molecules (B7-1, ICAM-1 and LFA-3) (TRICOM) vaccine work in preventing prostate cancer from coming back in patients who have undergone radical prostatectomy. Vaccines made from a gene-modified virus such as, rilimogene galvacirepvec and recombinant fowlpox-PSA(L155) / TRICOM vaccine, may help the body build an effective immune response to kill tumor cells. Giving vaccine after surgery may kill any remaining tumor cells.
    Location: 2 locations

  • Soy Bread Diet in Improving Immune Function in Participants with Prostate Cancer

    This phase II trial studies the effects of a soy bread diet in improving immune function in participants who are undergoing surgery for prostate cancer. Components found in soy foods may influence the immune system in a way that may be beneficial for prostate cancer prevention and survivorship.
    Location: Ohio State University Comprehensive Cancer Center, Columbus, Ohio

  • Repetitive Transcranial Magnetic Stimulation in Promoting Smoking Cessation in Patients with Stage I-IIIA Cancer

    This trial studies how repetitive transcranial magnetic stimulation works in increasing abstinence and decreasing cigarette consumption in patients with stage I-IIIA cancer. Repetitive transcranial magnetic stimulation uses magnetic pulses to temporarily stimulate specific areas of the brain. Using how repetitive transcranial magnetic stimulation may promote smoking cessation in cancer patients who smoke.
    Location: Medical University of South Carolina, Charleston, South Carolina

  • Home-Based Exercise Program in Studying Impact on Prognostic Biomarkers in Participants with Prostate Cancer

    This pilot trial studies the impact of a home-based exercise program on prognostic biomarkers in participants with prostate cancer. Several reports suggest that physical activity after a cancer diagnosis is associated with better cancer-specific and overall survival in individuals diagnosed with prostate cancer. A home-based exercise program may help doctors to learn the impact of exercise on blood markers associated with tumor development and the effect of exercise on the biology of prostate cancer, its impact on fatigue, and quality of life in participants with prostate cancer.
    Location: Cancer Therapy and Research Center at The UT Health Science Center at San Antonio, San Antonio, Texas

  • Low-Fat Diet and Fish Oil in Men on Active Surveillance for Prostate Cancer

    This randomized phase II trial will evaluate if a low-fat diet with fish oil has the potential to delay disease progression in patients with prostate cancer undergoing active surveillance.
    Location: 2 locations