Pediatric and Adolescent Solid Tumor Steering Committee
The Pediatric and Adolescent Solid Tumor Steering Committee (PASTSC) was established in 2011. PASTSC members include representatives from the Children's Oncology Group, pediatric and medical oncologists and other specialists, translational scientists, biostatisticians, patient advocates, and NCI staff.
The PASTSC works to promote the best clinical and translational science in the study of the extracranial solid tumors of children and youth by critically reviewing submitted phase 2 and phase 3 concepts for their rationale, design and priority. Concepts in brain and other central nervous system tumors are reviewed by the Brain Malignancies Steering Committee.
Clinical Trials Planning Meetings (CTPMs)
- Neuroblastoma – April 2012
The following are clinical trials that were approved at the concept stage by the Steering Committee:
|Trial ID||NCT ID||Trial Title|
|COG-ANBL1221||NCT01767194||Phase II Randomized Trial of Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Monoclonal Antibody Ch14.18 in Treating Younger Patients With Refractory or Relapsed Neuroblastoma|
|COG-ANBL12P1||NCT01798004||Pilot Study Using Myeloablative Busulfan/Melphalan (BuMel) Consolidation Following Induction Chemotherapy for Patients with Newly Diagnosed High-risk Neuroblastoma|
CCCT Contact: Wolf Lindwasser, Ph.D.