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Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

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Research

To transform the diagnosis and treatment of cancer using genomics, OCG implements research programs designed to illuminate cancer biology and generate rich community resources that benefit cancer researchers worldwide. Using a collaborative “team science” approach, OCG engages in three complementary sub-disciplines within cancer genomics: genome sequencing, functional genomics, and computational genomics.

  • Genomics Gene Regulation

    Cancer Genome Sequencing

    Cancer genome sequencing identifies alterations in cancer that contribute to cancer growth, metastasis, and recurrence. OCG's programs for characterizing cancers include The Cancer Genome Atlas and TARGET.

  • Florescent dyes highlight genes of cells growing in multi-well plates.

    Functional Genomics Research

    Functional genomics studies the role of particular cancer genes and pathways in the development and progression of cancer and harnesses that knowledge to develop therapeutic strategies against the disease. OCG's functional genomics research includes the Cancer Target Discovery and Development (CTD²) Network and the Human Cancer Models Initiative (HCMI).

  • image of someone in front of three computer screens

    Computational Genomics Research

    Computational genomics uses statistical and computational approaches to derive insights from big data on cancer. OCG's work in this field helps develop tools for interpreting large, high-throughput datasets and make data secure and accessible for the research community.

  • Infographic displaying the Genome Characterization Pipeline

    OCG's Genome Characterization Pipeline

    NCI’s Genome Characterization Pipeline is an efficient workflow that transforms cancer tissue samples into rich, publicly available genomic and clinical data. By partnering with foremost experts in tissue processing, bioinformatics, and data science, OCG produces and shares high quality, harmonized raw and processed data with researchers worldwide.

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