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Pediatric and Adolescent Solid Tumor Steering Committee

The Pediatric and Adolescent Solid Tumor Steering Committee (PASTSC) was established in 2011. PASTSC members include representatives from the Children's Oncology Group, pediatric and medical oncologists and other specialists, translational scientists, biostatisticians, patient advocates, and NCI staff.

Mission Statement

The PASTSC works to promote the best clinical and translational science in the study of the extracranial solid tumors of children and youth by critically reviewing submitted phase 2 and phase 3 concepts for their rationale, design and priority. Concepts in brain and other central nervous system tumors are reviewed by the Brain Malignancies Steering Committee.

Roster of Pediatric and Adolescent Solid Tumor Steering Committee (PASTSC) members

PASTSC Activities

Clinical Trials Planning Meetings (CTPMs)

Relevant Publications

Clinical Trials

The following are clinical trials that were approved at the concept stage by the Steering Committee:

Trial ID NCT ID Trial Title
COG-ANBL1221 NCT01767194 Phase II Randomized Trial of Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Monoclonal Antibody Ch14.18 in Treating Younger Patients With Refractory or Relapsed Neuroblastoma
COG-ANBL12P1 NCT01798004 Pilot Study Using Myeloablative Busulfan/Melphalan (BuMel) Consolidation Following Induction Chemotherapy for Patients with Newly Diagnosed High-risk Neuroblastoma

Find all NCI-sponsored clinical trials.

CCCT Contact: Wolf Lindwasser, Ph.D.